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It keeps Chelsea eight points clear at the summit despite 4-0 wins for both Arsenal and Manchester United.
Leicester City assuaged their relegation fears with a gutsy 3-2 win over Brighton, while Everton beat bottom side Crystal Palace 3-0 and West Ham got past Spurs 2-0.
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Chelsea produced the perfect response to their first defeat of the season with a comeback 2-1 win against Manchester City.
The Blues were beaten for the first time in all competitions in midweek, as Vivianne Miedema struck twice to help City to a 2-0 win in the first leg of their Champions League tie.
It looked like City would make it two wins in a row when Kerolin marked a stellar first half with a goal just after the half-hour mark.
It could have been two, only for Jess Park to see her strike chalked off after the whistle was blown a second earlier for a foul on Kerolin, leaving City less than impressed.
Chelsea struck back through Aggie Beever-Jones just after the break, and despite a strong second half from Khiara Keating, Erin Cuthbert got the winner in second-half stoppage time.
Arsenal avenged their FA Cup defeat to Liverpool with a thumping 4-0 victory over the Reds at the Emirates.
Mariona Caldentey made it 3-0 just before half time, and another own goal from Matthews after the break sealed an emphatic victory.
Manchester United also bounced back from defeat to Liverpool with a 4-0 demolition of Aston Villa.
The Villans remain just a point above the relegation zone and face back-to-back away trips to Liverpool and Spurs in desperate need of points.
Leicester City pulled six points clear of the drop with a 3-2 win over Brighton & Hove Albion.
The Foxes were forced to endure a nervy final ten minutes despite being 3-0 up at half time, when two second-half strikes almost saw the visitors steal a point.
Kelly Gago sealed victory late on to lift Everton 10 points clear of Palace at the bottom of the table.
Defeat keeps Palace rooted to the foot of the table, and face Arsenal, Chelsea, and Manchester City amongst their final five matches meaning home matches against West Ham and Leicester could be pivotal to their survival chances.
West Ham continued their strong recent form with a 2-0 win over London rivals Spurs.
A Josefine Rybrink own goal put the Hammers ahead early in the first half and Viviane Asseyi sealed the victory late in the second half.
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