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The 32-year-old scored the opening goal at the Etihad Stadium and provided the assist for Dominik Szoboszlai's first-half strike.
The win in Manchester saw Salah become the first player in Premier League history to achieve more than 40 goal involvements in two different seasons (2017/18 and 2024/25).
Salah now has 42 to his name following his assist in the 2-0 win over Newcastle United last week.
Salah is also the first player in the Premier League to score 25 goals and provide 15 assists in the same season.
His current tally is 25 goals with 17 assists in the top flight with 10 matches left to play.
On a Liverpool level, Salah now has the most assists for the Reds in a single Premier League season.
That record was broken with his assist against Man City and extended with the assist in the win over Newcastle.
The win over City also saw Salah become the first player to score and assist in both Premier League matches against the reigning champions.
He also became the first player since Lionel Messi in 2014/15 to score and assist in 11 league matches across Europe's top five leagues.
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One final record that Salah broke was becoming the first player this season to achieve 50 goal contributions in all competitions across Europe's top five leagues.
The Egyptian now has 52 to his name thanks to his performances against Man City and Newcastle and will have the chance to add to that when Liverpool face Paris Saint-Germain in the Champions League on Wednesday.
Salah had the chance to add another Premier League record to his name earlier in the season.
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