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The Reds will need to respond after Arsenal's win over Leicester on Saturday cut their lead down to four points.
Arne Slot will be on the touchline despite his red card after the final whistle at Goodison Park, and he will be hoping his side can bounce back from the disappointment of dropping two points against Everton as they take on a struggling Wolves side.
Vitor Pereira's team sits just two points above the Premier League's relegation zone, although a win last time out against Aston Villa will have boosted their confidence as they look to defy the odds on Merseyside today.
Here, Liverpool.com has picked out all of the information that you need to know, including the kick-off time, TV details, highlights and early team news.
We'll start with kick-off details for the UK and US.
What time is kick-off?
Yes, fans in the UK will be able to watch the game live.
It will be broadcast on Sky Sports Main Event and Sky Sports Premier League, with coverage getting underway at 1pm, and it will be available for streaming on Sky Go, or through the Sky Sports app if you get your subscription through a different provider.
Fans in the US will also be able to watch live.
The game will be available on TV via the USA Network, while it can also be streamed on NBC.com.
Want to watch more live sports?
Peacock offers plans starting at $7.99 so you can stream live sports like NFL, Premier League, and Big Ten Football.
Where can I catch the highlights?
For more news relating to Everton, visit our sister site EFC Live.