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Alexander-Arnold is facing an extended spell on the sidelines with the ankle injury sustained in their Champions League exit against Paris Saint Germain on Tuesday.
It leaves Slot without a recognised right-back this weekend at Wembly as both Conor Bradley and Joe Gomez are still recovering from their own issues.
Slot has hinted that Quansah - who replaced Alexander-Arnold against PSG - will most likely fill in, having spent much of the campaign on the outside looking in after losing his place as starting centre-back at half-time of the season opener against Ipswich.
The Dutchman, then on Premier League debut, wasn't happy at his defender 'losing too many duels'.
“He did really well the last few times he had to play for us, even in a position he is not completely used to at right full-back but he has the qualities to play in that position.
“He is strong, fast, very comfortable with the ball and it gives us an extra quality in terms of set-pieces because he was the one who was this far [measuring inches with his fingers] of us qualifying for the next round by heading the ball against the post [in the second leg against PSG].”
While Slot has no qualms about going with Quansah on Sunday - Curtis Jones has been mentioned in some quarters as an alternative - the blow of losing Alexander-Arnold and his ability on the ball cannot be under-estimated.
“Trent is not available.
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