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Alisson Becker returns in goal after a concussion that was suffered on international duty for Brazil nearly a month ago.
The Northern Ireland international suffered a hamstring injury as a substitute in the 2-2 draw at Aston Villa in February and only returned as a second-half sub in the 3-2 loss at Fulham last week.
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On the opposite flank, Kostas Tsimikas comes in at left-back for Andy Robertson as Ibrahima Konate partners captain Virgil van Dijk in the centre of the back four.
Curtis Jones is pushed back into midfield as Dominik Szoboszlai is given a rest.
Luis Diaz returns for Cody Gakpo on the left side of the attack as Mohamed Salah, fresh from the confirmation of his new, two-year contract extension on Friday, starts on the right side as aims to add to his 27 Premier League goals this term.
It's unclear at this stage of the Uruguay international has suffered an injury
Liverpool: Alisson; Bradley, Konate, Van Dijk, Tsimikas; Gravenberch, Mac Allister; Salah, Jones, Diaz; Jota